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Index > Protein center > Sfrp4(Gene name) > Rat
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  • Sfrp4 (Gene name),
  • Secreted frizzled-related protein 4 (Protein name ),  SFRP4_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Sfrp4(Ddc4;Frp);
    Protein name:
    Secreted frizzled-related protein 4(sFRP-4);
    Alternative:
    DDC-4 protein;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    348
    Sequence:
    50:
    MLLSILVALC | LCVRLALGVR | GAPCEAVRIP | MCRHMPWNIT | RMPNHLHHST | 
    100:
    QENAILAIEQ | YEELVDVNCS | SVLRFFLCAM | YAPICTLEFL | HDPIKPCKSV | 
    150:
    CQRARDDCEP | LMKMYNHSWP | ESLACDELPV | YDRGVCISPE | AIVTDLPEDV | 
    200:
    KWIDITPDMM | VQERSFDADC | KHLSPDRCKC | KKVKPTLATY | LSKNYSYVIH | 
    250:
    AKIKAVQRSG | CNEVTTVVDV | KEIFKSSSPI | PRTQVPLITN | SSCQCPHILP | 
    300:
    HQDVLIMCYE | RRSRMMLLEN | CLVEKWRDQL | SRRSTQWEER | LQEQQRTTQD | 
    348:
    KKQIASRTSR | SNPPKPKGRS | PASKPASPKK | NIKARSAPKK | SNPKKSTS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat sFRP-4
    Cat.:
    E1650m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat sFRP-4
    Cat.:
    E1650h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat sFRP-4
    Cat.:
    E1650r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat sFRP-4
    Cat.:
    U1650h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat sFRP-4
    Cat.:
    U1650m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat sFRP-4
    Cat.:
    U1650r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat sFRP-4
    Cat.:
    P1650Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat sFRP-4
    Cat.:
    P1650Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat sFRP-4
    Cat.:
    P1650Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat sFRP-4
    Monoclonal Antibody for Rat sFRP-4
    Monoclonal Antibody for Rat sFRP-4
    Protein for Rat sFRP-4
    Protein for Rat sFRP-4
    Protein for Rat sFRP-4

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    References
    1. 1.
      "DDC-4, an apoptosis-associated gene, is a secreted frizzled relative."
      Wolf V. , Ke G. , Dharmarajan A.M. , Bielke W. , Artuso L. , Saurer S. , Friis R.R.
      FEBS Lett.417:385-389(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Corpus luteum.
    2. 2.
      "Transcriptional activity of the promoter region of rat frizzled-related protein gene."
      Yam J.W.P. , Chan K.W. , Wong V.K.W. , Hsiao W.L.W.
      Biochem. Biophys. Res. Commun.286:94-100(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      strain: Fischer.
      tissue: Fibroblast.
      tissue: Liver.
    3. 3.
      "Apoptosis-associated gene expression in the corpus luteum of the rat."
      Guo K. , Wolf V. , Dharmarajan A.M. , Feng Z. , Bielke W. , Saurer S. , Friis R.
      Biol. Reprod.58:739-746(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-140
      strain: Sprague-Dawley.
    4. 4.
      "Differential expression of secreted frizzled-related protein 4 in decidual cells during pregnancy."
      Fujita M. , Ogawa S. , Fukuoka H. , Tsukui T. , Nemoto N. , Tsutsumi O. , Ouchi Y. , Inoue S.
      J. Mol. Endocrinol.28:213-223(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 190-347;DEVELOPMENTAL STAGE
      strain: Wistar.
      tissue: Uterus.
    5. 5.
      "Expression and localization of secreted frizzled-related protein-4 in the rodent ovary: evidence for selective up-regulation in luteinized granulosa cells."
      Hsieh M. , Mulders S.M. , Friis R.R. , Dharmarajan A. , Richards J.S.
      Endocrinology144:4597-4606(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INDUCTION
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